Population genetic diversity of Schistosoma japonicum arises from the host switching in the life cycle.

ABSTRACT:

Background

Schistosoma japonicum is a multi-host parasite, including asexual amplification in snail hosts and sexual reproduction in mammalian hosts. The genetic diversity of S. japonicum by host switching is less understood, which could help elucidate the genetic evolution of S. japonicum under host pressure and provide instruction for host sampling and the infection pattern to make S. japonicum infection models.

Methods

Different developmental stages of S. japonicum were collected and genotyped with 24 microsatellite loci, including 345 cercariae from naturally infected snails and 472 and 540 adult worms from artificially infected mice and rabbits, separately. The genetic distribution of S. japonicum within and among hosts by different sampling was assessed, and the geneti

SUBMITTER: Long J 

PROVIDER: S-EPMC11949366 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature