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Association between urinary albumin-to-creatinine ratio within normal range and kidney stones in U.S. adults: a cross-sectional observational study.


ABSTRACT:

Background

Kidney stones are a major public health concern, and their prevalence has increased significantly in recent decades. While urinary albumin-to-creatinine ratio (UACR) is a recognized marker for kidney disease, its relationship with kidney stones, especially within the normal UACR range, remains unclear. The purpose of this study was to investigate the association between UACR levels within the normal range and the risk of developing kidney stones.

Methods

We analyzed data from the National Health and Nutrition Examination Survey (NHANES) conducted from 2009 to 2018, focusing on adults aged 20 years and older with available UACR data. Using weighted multivariable logistic regression and restricted cubic spline (RCS) models, we assessed the relationship between UACR

SUBMITTER: Du YZ 

PROVIDER: S-EPMC11949821 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature