High heterogeneity in the size distribution of the micellar fraction from in vitro digestions: sample preparation and reporting recommendations.

ABSTRACT:

Background

Understanding the size and surface charge (ζ-potential) of particles in the mixed micellar fraction produced by in vitro digestion is crucial to understand their cellular absorption and transport. The inconsistent presentation of micellar size data, often limited to average particle diameter, makes comparison of studies difficult. The present study aimed to assess different size data representations (mean particle diameter, relative intensity- or volume-weighted size distribution) to better understand physiological mixed micelle characteristics and to provide recommendations for size reporting and sample handling.

Results

Dietary compounds (RRR-α-tocopherol, retinyl-palmitate, β-carotene, curcumin and naringenin) underwent a simplified in vitro digestion, whereas

SUBMITTER: Will R 

PROVIDER: S-EPMC11949856 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature