Virulence and resistance gene analysis of Rothia nasimurium by whole gene sequencing.

ABSTRACT: A batch of sheep in a sheep farm in Xinjiang, China, died suddenly; a bacterial strain was isolated from the abdominal fluid of the sick and dead sheep, and identified as Rothia nasimurium by 16S sequencing, and the strain Y1 was subjected to drug sensitivity test with Draft gene sequencing. The results of the drug sensitivity test revealed the strain's resistance to 9 antibiotics, with sensitivity exhibited solely towards amikacin and vancomycin. Phylogenetic tree analysis confirmed that it was related to Rothia nasimurium strain E1706032 and Rothia sp.SD9660Na. The draft genome sequencing results showed that the total length of the gene was 2,387,685 bp, and the GC content was 59.35%. VFDB database analysis identified 112 annotated genes in Y1, including those related to bacterial adhesi

SUBMITTER: Lu Z 

PROVIDER: S-EPMC11950441 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature