Brain structural magnetic resonance imaging predictors of brief intervention response in individuals with alcohol use disorder.

ABSTRACT:

Aims

Magnetic resonance imaging (MRI) studies have identified brain structural predictors of treatment response in individuals with alcohol use disorder (AUD) but with varying findings and primarily in male veterans. The present study investigated cortical surface area and thickness (CT) as predictors of brief intervention response in community-based adults with AUD.

Methods

Sixty-five non-treatment-seeking adults with AUD (44.6% male, aged 33.2 ± 1.3 years) underwent an MRI and received a brief intervention comprising personalized feedback and motivational interviewing, with follow-up ~6-8 weeks later to quantify changes in drinks/week (DPW), the primary outcome. Eighteen bilateral a priori regions of interest (ROIs) were used to predict DPW at follow-up, adjusting for base

SUBMITTER: Hargreaves TL 

PROVIDER: S-EPMC11950530 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature