Outcomes of Fecal Microbiota Transplantation for <i>Clostridioides difficile</i> Infection in South Australia.

ABSTRACT:

Background

Fecal microbiota transplantation (FMT) sourced from a bank of prescreened anaerobically processed frozen donor stool has been available in South Australia since 2013. This study aimed to evaluate the real-world clinical and safety outcomes of FMT for recurrent, refractory, and/or severe or fulminant Clostridioides difficile infection (CDI) facilitated via this centralized facility.

Methods

Donor screening test data were prospectively collected on all donors who passed prescreening evaluations between April 2013 and August 2023. The South Australian FMT for CDI database prospectively recorded outcomes for consecutive patients who underwent FMT for CDI from August 2013 to May 2023 in South Australia.

Results

An overall 98 potential donors passed prescr

SUBMITTER: Tucker EC 

PROVIDER: S-EPMC11950531 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature