Assessment of Age-Related Differences in Lower Leg Muscles Quality Using Radiomic Features of Magnetic Resonance Images.

ABSTRACT: Sarcopenia, characterised by a decline in muscle mass and strength, affects the health of the elderly, leading to increased falls, hospitalisation, and mortality rates. Muscle quality, reflecting microscopic and macroscopic muscle changes, is a critical determinant of physical function. To utilise radiomic features extracted from magnetic resonance (MR) images to assess age-related changes in muscle quality, a dataset of 24 adults, divided into older (male/female: 6/6, 66-79 years) and younger (male/female: 6/6, 21-31 years) groups, was used to investigate the radiomics features of the dorsiflexor and plantar flexor muscles of the lower leg that are critical for mobility. MR images were processed using MaZda software for feature extraction. Dimensionality reduction was performed using prin

SUBMITTER: Shiiba T 

PROVIDER: S-EPMC11950595 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature