Early age-related changes to articular cartilage T_1ρ in hips with Legg-Calve-Perthes disease deformity.

ABSTRACT:

Objective

To determine whether the relationship between cartilage T_1ρ relaxation time and age during adolescence and young adulthood is different in hips with Legg-Calvé-Perthes disease (LCPD) deformity compared to hips without LCPD deformity.

Design

We recruited 17 participants with LCPD deformity and 15 control participants aged 10-25 years in this frequency-matched cohort study. Quantitative magnetic resonance images were obtained for both hips in LCPD participants and one hip from each control using a T_1ρ MAPSS sequence. The average T_1ρ relaxation time in the weight-bearing articular cartilage was calculated, and we tested the interacting effects of age and participant group (LCPD vs non-LCPD) or subgroup (control, contralateral LCPD, sph

SUBMITTER: Johnson LG 

PROVIDER: S-EPMC11950756 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature