A persistent sink reservoir as a potential source of <i>Pseudomonas aeruginosa</i> infections in pediatric oncology patients.

ABSTRACT:

Objective

Outbreaks of Pseudomonas aeruginosa infections have been linked to water-related sources. We describe the investigation of a suspected outbreak of five P. aeruginosa infections in pediatric oncology patients in 2021 that triggered a retrospective review and prospective monitoring of additional cases, environmental sampling, and bacterial genomic analysis.

Setting and patients

Pediatric oncology center.

Methods

Medical records of patients with P. aeruginosa were reviewed and staff were interviewed to identify common exposures. Environmental samples were cultured for P. aeruginosa. Patient and environmental isolates underwent whole genome sequencing and core genome multi-locus sequence typing (cgMLST) and sequences were added to a p

SUBMITTER: Richards L 

PROVIDER: S-EPMC11951235 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature