Impact of negative lymph node removal on survival in esophageal cancer: a systematic review and meta-analysis.

ABSTRACT:

Background

Recent studies have reported that a high number of negative lymph nodes (NLNs) removed can be associated with improved survival in esophageal cancer( EC) after surgery; however, the effect size of a high number of removed NLNs on survival rates has been reported to vary, which may be due to the small sample size of early studies. This meta-analysis aimed to evaluate the effect of the high number of NLNs removed on the survival rate of patients with EC after surgery.

Methods

We searched PubMed, Embase, Scopus, Web of Science, and Google Scholar databases with relevant Mesh terms to find studies that investigated the effect of the number of NLNs resected on the survival of EC patients after surgery until February 17, 2025. This systematic review was conducted based

SUBMITTER: Bahardoust M 

PROVIDER: S-EPMC11951649 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature