High levels of serum uric acid are associated with microvascular complications in patients with long-term diabetes.

ABSTRACT:

Aims

To assess the association between serum uric acid (SUA) level and the prevalence of diabetic retinopathy (DR) and chronic kidney disease (CKD) in patients with long-term diabetes.

Methods

A cross-sectional analysis was conducted involving diabetic patients from Shanghai General hospital during October 2018 and October 2021. Participants underwent measurements of SUA, renal function test and DR assessments via fundus photography. Multivariable ordinal logistic regression models assessed odd ratios (ORs) and 95% confidence intervals (95% CIs) for the progression of DR and CKD. Receiver operating characteristics (ROC) curves identified SUA thresholds, categorizing participants into low and high SUA groups.

Results

Among the 1015 patients with diabetes, SUA levels we

SUBMITTER: Wang H 

PROVIDER: S-EPMC11951721 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature