Prognostic effect of neutrophil percentage-to-albumin ratio (NPAR) on all-cause and cardiovascular mortality in diabetic kidney disease (DKD): NHANES 1999-2018.

ABSTRACT:

Background

This study aimed to evaluate the associations between neutrophil percentage-to-albumin ratio (NPAR) and both all-cause and cardiovascular mortality in diabetic kidney disease (DKD) patients.

Methods

The data for this study were sourced from the National Health and Nutrition Examination Survey (NHANES) 1999-2018. Weighted logistic regression, Cox proportional hazards model, and Fine-Gray competing risk model were used to assess the association between NPAR and both all-cause and cardiovascular mortality in DKD patients.

Results

A total of 2,699 participants were enrolled in this study. Cox regression analysis revealed that elevated NPAR levels were associated with a higher risk of all-cause mortality in all participants (HR: 2.17, 95%CI: 1.83-2.58). Meanwhil

SUBMITTER: Tan J 

PROVIDER: S-EPMC11951754 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature