In vitro anti-inflammatory and in silico anti-viral assessment of phytoconstituents in polyherbal Ayurvedic formulation 'Arogyamrita Kwath'.

ABSTRACT:

Background

Arogyamrita Kwath (AMK) is a polyherbal decoction comprising ten medicinal plants, viz., Albizia lebbeck, Andrographis paniculata, Tinospora cordifolia, Adhatoda vasica, Solanum xanthocarpum, Curcuma longa, Glycyrrhiza glabra, Terminalia bellirica, Withania somnifera and Trachyspermum ammi. The plants of the AMK formulation are traditionally used for the treatment of inflammation and respiratory ailments, but no scientific evidence has been reported so far for this formulation.

Objectives

To evaluate anti-inflammatory activity of AMK formulation in vitro and its fractions and to predict in silico anti-viral activity of identified potential phytoconstituents.

Materials and methods

The MTT cell cytotoxicity assay, nitric oxide (NO) inhibition assay and cytoki

SUBMITTER: Dey A 

PROVIDER: S-EPMC11951999 | biostudies-literature | 2025 Mar-Apr

REPOSITORIES: biostudies-literature