MiRNA profile in pancreatic neuroendocrine tumors: Preliminary results.

ABSTRACT:

Objective

Our understanding of the pathophysiology of pancreatic neuroendocrine tumors (PanNETs) remains incomplete, largely due to their historically underestimated incidence and the perception of these tumors as rare and slow-growing cancers. Additionally, conventional reliance on histological examination alone is gradually being supplemented by the exploration and introduction of molecular biomarkers, such as microRNAs (miRNAs). As miRNAs modulate the expression of multiple genes and pathways involved in the tumorigenesis of PanNETs, these biomarkers hold considerable promise for diagnosis and prognosis applications. In this study, we aimed to identify miRNAs as tissue markers associated with the diagnosis of PanNETs.

Methods

We conducted a case-control study including: 7

SUBMITTER: Ciobanu OA 

PROVIDER: S-EPMC11952036 | biostudies-literature | 2025 Jan-Mar

REPOSITORIES: biostudies-literature