Longitudinal changes in functional connectivity networks in the first year following stroke.

ABSTRACT: The functional organization of the brain consists of multiple subsystems, or modules, with dense functional communication within modules (i.e., visual, attention) and relatively sparse but vital communications between them. The two hemispheres also have strong functional communications, which presumably supports hemispheric lateralization and specialization. Subsequent to stroke, the functional organization undergoes neuroplastic changes over time. However, empirical longitudinal studies of human subjects are lacking. Here we analyzed three large-scale, whole-brain resting-state functional MRI connectivity measures: modularity , hemispheric symmetry (based on system segregation ), and homotopic connectivity in a group of 17 participants at 1-month, 3-months, and

SUBMITTER: Tao Y 

PROVIDER: S-EPMC11952386 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature