Focal Infrared Neural Stimulation Propagates Dynamical Transformations in Auditory Cortex.

ABSTRACT:

Significance

Infrared neural stimulation (INS) has emerged as a potent neuromodulation technology, offering safe and focal stimulation with superior spatial recruitment profiles compared to conventional electrical methods. However, the neural dynamics induced by INS stimulation remain poorly understood. Elucidating these dynamics will help develop new INS stimulation paradigms and advance its clinical application.

Aim

In this study, we assessed the local network dynamics of INS entrainment in the auditory thalamocortical circuit using the chronically implanted rat model; our approach focused on measuring INS energy-based local field potential (LFP) recruitment induced by focal thalamocortical stimulation. We further characterized linear and nonlinear oscillatory LFP activity

SUBMITTER: Coventry BS 

PROVIDER: S-EPMC11952546 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature