Associations between fecal contamination of the household environment and enteric pathogen detection in children living in Maputo, Mozambique.

ABSTRACT: Environmental exposure to enteric pathogens is generally assessed using fecal indicators but relationships between markers of fecal contamination and actual exposure to enteric pathogens remain poorly characterized. We investigated whether Escherichia coli and two human fecal markers (HF183 and Mnif) in urban Mozambican household soil and drinking water were associated with detection in child stool of eight bacteria, three viruses, and three protozoa measured by multiplex reverse-transcription PCR and soil transmitted helminths assessed by microscopy. We used mixed-effects logistic regression with marginal standardization to obtain a pooled estimate of the overall indicator-pathogen relationship while simultaneously estimating pathogen-specific associations that accounted for assess

SUBMITTER: Holcomb DA 

PROVIDER: S-EPMC11952620 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature