Surgical ablation in patients with atrial fibrillation and left ventricular dysfunction: A systematic review and meta-analysis.

ABSTRACT:

Background

Atrial fibrillation (AF) and left ventricular dysfunction (LVD) are common conditions that often coexist, with about 25% of patients in NYHA classes I-II having AF. Efficacy and safety of surgical ablation (SA) in this population remains unclear.

Methods

We aimed to perform a single-arm meta-analysis to assess the outcomes of standalone and concomitant SA in adult patients with AF and LVD. We searched PubMed, Scopus and the Cochrane Library. Endpoints of interest were maintenance of sinus rhythm, freedom from anti-arrhythmic drug (AAD) use, change in LVEF, 30-day mortality, 1 year mortality and major procedural complications. We calculated pooled proportions or means for binary and continuous endpoints, respectively, with a 95 % confidence interval (CI).

SUBMITTER: Consoli LN 

PROVIDER: S-EPMC11952843 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature