Strain-dependent emergence of aminoglycoside resistance in <i>Escherichia coli</i> biofilms.

ABSTRACT: In most Earth environments, bacteria predominantly exist within surface-associated communities known as biofilms, where they are embedded in an extracellular matrix. These collective structures play a critical role in bacterial physiology and significantly shape their evolutionary trajectories, contributing to the development of antimicrobial resistance and enhancing bacterial resilience to treatments, with profound implications for public health. This study assessed the impact of the biofilm lifestyle on the emergence of resistance to gentamicin, an aminoglycoside antibiotic, in one laboratory reference strain and seven Escherichia coli isolates from food-processing environments. Throughout a one-month evolution experiment, we observed that certain strains showed a markedly higher

SUBMITTER: Charron R 

PROVIDER: S-EPMC11952850 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature