The Impact of Childhood Maltreatment on Central Pain Processing in Individuals With Psychosis.

ABSTRACT:

Introduction

Exposure to childhood maltreatment can contribute to multiple behavioral and clinical manifestations, including the development of psychotic illnesses and pain-related abnormalities. Aberrant pain perception in individuals with psychosis may be associated with the worsening psychiatric symptoms, including an increase in mood episodes and a higher risk for suicidality. Despite the multiple connections between psychosis, pain, and childhood maltreatment, the combined investigation of these three domains remains limited.

Methods

In this study, patients with schizophrenia (SZ, n = 20) or bipolar I disorder (BD, n = 24) and healthy controls (HC, n = 24) underwent a comprehensive clinical evaluation followed by quantitative sensory testing (QST), where behavioral sens

SUBMITTER: Cay M 

PROVIDER: S-EPMC11952974 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature