Poor sleep quality was associated with increased plasma aldosterone concentration in community dwellers, a cross-sectional study.

ABSTRACT: Sleep is implicated in circulating aldosterone, whereas effects of overall sleep quality are not characterized. Therefore, we explored relationship of sleep quality with plasma aldosterone concentration (PAC) in general population. We evaluated sleep quality using Pittsburgh sleep quality index (PSQI) and measured PAC in adults cross-sectionally. We divided participants into very good, fairly good, fairly bad and very bad sleepers, compared PAC and log-PAC, and applied linear regression to examine association of PSQI score with log-PAC, in total, gender- and age-stratified (young, middle-aged and old) participants. Sensitivity analysis were performed by excluding hypertension, sleep disordered breathing (SDB), or both. Among 29,499 participants, PAC showed significant increase from very go

SUBMITTER: Li X 

PROVIDER: S-EPMC11953333 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature