Asymmetric S=N-embedded polyaromatic construction via enantioselective Pd-catalyzed C-H activation.

ABSTRACT: Heteroatom-doped polyaromatic hydrocarbons show great potential for advancing photoelectric materials. S^VI=N doping, characterized by soft-hard atom binding, donor-acceptor transmission, and chiroptical tuning, provides a powerful approach for further optimizing the performance and functionality of these materials. However, the introduction of chiral sulfur(VI) has been a formidable challenge due to the intricate enantioselective discrimination and embedded linkages with the heteroatoms in the polyaromatic systems. Herein, we establish an enantioselective Pd-catalyzed desymmetrization of diaryl sulfoximines and sulfondiimines to access the chiral S^VI=N-doped heterocycles with high yields and enantioselectivities. The flexibility and rigidity of the molecule has a dist

SUBMITTER: Zeng D 

PROVIDER: S-EPMC11953408 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature