Breast cancer assessment under neoadjuvant systemic therapy using thoracic photon-counting detector computed tomography in prone position: a pilot study.

ABSTRACT:

Background

Accurate assessment of treatment response to neoadjuvant systemic therapy (NAST) in breast cancer is important prior to surgery. We aimed at evaluating the feasibility of thoracic photon-counting detector computed tomography (PCCT) in assessing treatment response in breast cancers following NAST.

Methods

We retrospectively included patients with newly diagnosed breast cancer who received contrast-enhanced thoracic PCCT in prone position before and after NAST. Three experienced radiologists measured tumor size, tumor area, iodine uptake within tumors, number of suspicious breast lesions and of suspicious axillary lymph nodes before and after NAST. We compared the initial tumor size to contrast-enhanced magnetic resonance imaging (MRI), the residual tumor size after

SUBMITTER: Neubauer C 

PROVIDER: S-EPMC11953491 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature