Chest compression synchronized ventilation during prolonged experimental cardiopulmonary resuscitation improves oxygenation but may cause pneumothoraces.

ABSTRACT:

Background

Chest compression synchronized ventilation (CCSV) has been proposed to provide superior ventilation and haemodynamics during cardiac arrest (CA) compared to conventional asynchronous ventilation and compressions. We compared arterial gas exchange, pH, lactate levels and haemodynamics between CCSV and manual asynchronous ventilation during prolonged experimental CA.

Methods

We randomized 30 pigs (weight ca. 55 kg) to receive CCSV with a MEDUMAT Standard² ventilator or a manual bag valve targeting 10-12 ventilations per minute. Chest compressions were provided with a Lucas® 2 device. Arterial samples were drawn every 5 min and monitoring was recorded continuously. The animals underwent chest CT scans after death.

Results

The median intra-arrest art

SUBMITTER: Kopra J 

PROVIDER: S-EPMC11953954 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature