Stereotactic body radiotherapy for lung oligometastatic prostate cancer: An international retrospective multicenter study.

ABSTRACT:

Background

Management of prostate cancer (PCa) patients with lung oligometastases remains unclear in the absence of published data.

Objective

The aim of this study was to evaluate the efficacy of Stereotactic Body Radiotherapy (SBRT) in this setting.

Design setting and participants

We conducted a multicenter retrospective study that included 35 PCa patients treated with SBRT for lung oligometastases in 7 centers across 3 countries.

Outcome measurements and statistical analysis

The efficacy was evaluated by the progression free-survival (PFS), defined as pre-SBRT PSA + 25 % or nadir PSA + 25 % and + 2 ng/mL or radiological progression if it occurred before biochemical progression. The local recurrence free-survival (LRFS), distant metastases free-survival (DMFS)

SUBMITTER: Roge M 

PROVIDER: S-EPMC11953985 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature