A meta analysis of efficacy and safety of nefopam for laparoscopic cholecystectomy pain management.

ABSTRACT:

Background

Nefopam is a safe analgesic with mild side effects including drowsiness, nausea, vomiting, and sweating. Nevertheless, research is scarce on the impact of nefopam in managing postoperative pain following laparoscopic cholecystectomy (LC), and the advantageous effects of nefopam remain unclear. In this research, the effectiveness of nefopam was compared to placebo for the treatment of postoperative pain following LC.

Methods

A literature search for randomized controlled trials (RCTs) was performed through June 2024 using online databases including Cochrane Library, PubMed/Medline, and Web of Science. The primary outcome assessed was the quality of postoperative patient pain, and the secondary outcome was side effects that occurred due to the use of nefopam. The Coc

SUBMITTER: Aleid AM 

PROVIDER: S-EPMC11954109 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature