Systematic review on serotypes distribution of pneumococcal pneumonia in adults and the elderly.

ABSTRACT:

Background

Pneumococcal pneumonia is a major cause of morbidity and mortality among adults, especially those over 65 years of age. Understanding pneumococcal serotype-specific epidemiology in adults and elderly is necessary to inform vaccination policies and to guide the inclusion of serotypes in pneumococcal vaccines. This study aimed to identify the serotypes causing pneumonia in the elderly.

Methods

A systematic review search was performed using the PubMed database from 1984 to 2020. The search was limited to articles written in English. Studies assessing pneumococcal pneumonia in adults were included. Meta-analysis, other systematic literature reviews and case-reports were excluded. Studies published after the introduction of vaccines (PPSV23 and PCVs) were included.

SUBMITTER: Mrabt F 

PROVIDER: S-EPMC11954302 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature