Differential fMRI neural synchrony associated with migraine during naturalistic stimuli with negative emotional valence.

ABSTRACT: Migraine is a common neurological disorder that impacts approximately 12% of the general population and is characterized by moderate to severe headaches, nausea, mood changes, and fatigue. It impacts lower-level visual and auditory processing, causing hypersensitivities that lead to heightened audiovisual multisensory integration. However, the impact of migraine on the processing of complex, audiovisual stimuli is still unclear. Additionally, migraine may induce hypersensitivities to emotional arousal and valence, though the relative significance of these factors remains unknown. The current study seeks to identify how migraine impacts synchronous neural processing of complex, audiovisual stimuli, and how this differs based on the emotional arousal and valence of the stimulus. To do so, we

SUBMITTER: Klamer K 

PROVIDER: S-EPMC11954307 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature