Integrative genomic analysis reveals shared loci for reproduction and production traits in Yorkshire pigs.

ABSTRACT:

Background

Improving reproductive performance in Yorkshire pigs, a key maternal line in three-way crossbreeding systems, remains challenging due to low heritability and historical selection pressures favoring production traits. Identifying pleiotropic genetic variants that influence both reproduction and production traits is crucial for understanding their genetic interplay and enhancing molecular breeding strategies.

Results

Genome-wide association studies (GWAS) using 2,764 individuals identified 264,660 significant loci associated with reproduction traits and 12,460 loci for production traits, with 73 independent signals, including genes such as SCLT1 and CAPN9. A total of 465,047 independent loci were identified, resulting in a genome-wide significance threshold of 2.15×

SUBMITTER: Wei R 

PROVIDER: S-EPMC11954345 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature