Glucagon change rate after glucose load: a potential key for tailoring treatment in gestational diabetes mellitus.

ABSTRACT: Gestational diabetes mellitus (GDM) is a known risk factor for both maternal and fatal complications. Glycemic control in pregnant women is important for preventing these complications. However, the need for insulin therapy in pregnant women is difficult to determine. This study focuses on glucagon, which provides new prospects due to advancement in the measurement assay method for type 2 diabetes. Investigating the dynamics of glucagon in pregnant women will help in the diagnosis of GDM and in identifying those requiring insulin treatment. A total of 58 pregnant women between 24 and 31 weeks of gestation underwent a 75-g glucose tolerance test at our institution between 2013 and 2015. The results showed differences in post-glucose and insulin levels between patients with and without GDM,

SUBMITTER: Joko S 

PROVIDER: S-EPMC11954775 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature