Risk factors and influence on neurodevelopmental outcomes of neonatal seizures in very low birth weight infants based on nationwide cohort.

ABSTRACT: We assessed the risk factors of neonatal seizures and their influences on neurodevelopment in very-low-birth-weight infants (VLBWIs). 16,279 VLBWIs born in 2013-2020 were included using Korean Neonatal Network data to assess the risk factors of neonatal seizures. 7,599 VLBWIs born in 2013-2018 and followed up at 18-24 months corrected age were included to assess the influence of seizures on mortality and any neurodevelopmental impairment (NDI) including blindness, deafness, cerebral palsy (CP), and mental and motor NDI based on Bayley test (NDI-Bayley). We also compared clinical factors between no NDI and any NDI groups after neonatal seizures. 1,430 infants (8.8%) had neonatal seizures. Significant risk factors for neonatal seizures were lower GA, male gender, congenital anomaly, small fo

SUBMITTER: Lee JA 

PROVIDER: S-EPMC11954959 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature