Profiles and natural drivers of antibiotic resistome in multiple environmental media in penguin-colonized area in Antarctica.

ABSTRACT: Profiles and driving mechanisms of antibiotic resistome in the polar region are important for exploring the natural evolution of antibiotic resistance genes (ARGs). Here, we evaluated the profiles of antibiotic resistome in multiple media on Inexpressible Island, Terra Nova Bay, Antarctica. Average concentrations of ARGs in intracellular DNA (iARGs) among water (3.98 × 10⁶ copies/L), soil (3.41 × 10⁷ copies/kg), and penguin guano (7.04 × 10⁷ copies/kg) were higher than those of ARGs in extracellular DNA (eARGs) among water (1.99 × 10⁴ copies/L), soil (1.75 × 10⁶ copies/kg), and penguin guano (8.02 × 10⁶ copies/kg). It was indicated that the transmission of ARGs across different media occurs with around 77.8% of iARGs from so

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC11955065 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature