Association between obstructive sleep apnea and multiple adverse clinical outcomes: evidence from an umbrella review.

ABSTRACT:

Background and objective

In recent years, there has been a notable rise in awareness regarding obstructive sleep apnea (OSA), and a significant number of potential OSA cases have been identified. Numerous studies have established associations between OSA and various adverse clinical outcomes. This umbrella review aims to summarize and evaluate the available evidence on the relationship between OSA and multiple adverse clinical outcomes.

Methods

PubMed, Embase, and Web of Science databases were systematically searched from inception to September 2023. The AMSTAR and GRADE were used to evaluate the quality of meta-analysis literature and classify the quality of literature evidence. Furthermore, the size of the effect size of the association between OSA and adverse clinical out

SUBMITTER: Wang Q 

PROVIDER: S-EPMC11955449 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature