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Efficacy of Jiedu formula as adjuvant therapy for early recurrence of hepatocellular carcinoma after radical surgery: a propensity score matching study.


ABSTRACT:

Objective

To investigate the clinical efficacy of using a Jiedu formula as an adjunctive therapy in patients with hepatocellular carcinoma (HCC) after hepatectomy.

Methods

In total, 354 patients were included in this study. All patients were categorized into the traditional herbal medicine (THM) group (n =115) or the non-THM treatment (nTHM) group (n =239), with the Jiedu formula administered twice a day to the patients in the THM group. The primary outcome was recurrence-free survival (RFS). Univariate and multivariate Cox regression analyses were performed to identify the prognostic factors associated with RFS. Then, the high risk of recurrence among patients was identified, and propensity score matching (PSM) and RFS analysis were performed to analyze the pr

SUBMITTER: Qiuting F 

PROVIDER: S-EPMC11955764 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature