Intra-breath respiratory mechanics of prematurity-associated lung disease phenotypes in school-aged children.

ABSTRACT:

Background

Intra-breath oscillometry potentially offers detailed information regarding airway function, with increasing magnitude of difference between resistance and reactance at end-expiration to end-inspiration potentially associated with obstructive airway disease, but less is known about specific respiratory mechanics in preterm-born children using this methodology. We investigated whether different spirometry phenotypes of prematurity-associated lung disease (PLD) have specific intra-breath oscillometry features.

Methods

167 school-aged (7-12 years) children, 14 with prematurity-associated obstructive lung disease (POLD; forced expiratory volume in 1 s (FEV₁) 1/forced vital capacity (FVC)

SUBMITTER: Cousins M 

PROVIDER: S-EPMC11955913 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature