Indoor allergen exposure and its association to upper respiratory infections and pulmonary outcomes among children with asthma.

ABSTRACT:

Background

Certain environmental allergen exposures are more common in disadvantaged communities and may contribute to differences in susceptibility to upper respiratory infections (URIs).

Objectives

We examined associations between indoor allergens and: (1) URI; (2) URI + cold symptoms; (3) URI + cold symptoms + pulmonary eosinophilic inflammation (fraction of exhaled nitric oxide ≥20 ppb); and (4) URI + cold symptoms + reduced lung function (percent predicted forced expiratory volume in 1 second of <80%).

Methods

We used data from the Environmental Control as Add-on Therapy for Childhood Asthma (ECATCh) study. Allergen concentrations were measured in air (mouse) and settled dust (mouse, cockroach, dog, and cat). URI was determined by testing nasal mucus for upper re

SUBMITTER: Bhavnani D 

PROVIDER: S-EPMC11955957 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature