Improvements in endovascular stroke treatment workflow over 5 years: ESCAPE to ESCAPE-NA1.

ABSTRACT: Background and PurposeRapid treatment is a major determinant of outcome in acute ischemic stroke patients with large vessel occlusion. We used patient-level data from the ESCAPE and ESCAPE-NA1 trials to evaluate whether and to what extent workflow interval times have improved over time.MethodsData were derived from the ESCAPE and the ESCAPE-NA1 randomized trials. Workflow interval times and reperfusion quality were summarized using descriptive statistics and compared on a patient level between the two trials using the Wilcoxon rank sum test and Fisher's exact test. The effect of patient baseline characteristics, including patient age, sex and stroke severity as measured by the National Institutes of Health Stroke Scale, on workflow times was determined using linear regression.ResultsAll pa

SUBMITTER: Ospel JM 

PROVIDER: S-EPMC11955977 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature