Effect of Early-Life Lipid-Based Nutrient Supplement and Home Environment on Autonomic Nervous System Regulation at 9-11 Years: A Follow-Up of a Randomized Controlled Trial.

ABSTRACT: Nutrition and the home environment contribute to the development of the autonomic nervous system (ANS). However, no study has examined the long-term effects of prenatal and postnatal small-quantity lipid-based nutrient supplements (SQ-LNS) and home environment on ANS regulation. We investigated the effect of early-life SQ-LNS and home environment on ANS regulation at 9-11 years. Participants were children born to women who participated in a randomized controlled trial in Ghana from 2009 to 2014. Women were randomized to receive daily, from pregnancy until delivery, either SQ-LNS, multiple micronutrients (MMN) or iron and folic acid (IFA) followed by SQ-LNS, MMN or placebo, respectively, until 6 months postpartum. Infants in the SQ-LNS group received SQ-LNS from 6 to 18 months. Quality of h

SUBMITTER: Aryee LMD 

PROVIDER: S-EPMC11956065 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature