Changes in peripapillary microvasculature and retinal nerve fibre layer in diabetes and diabetic retinopathy using optical coherence tomographic angiography: a community-based, cross-sectional study.

ABSTRACT:

Objective

To evaluate changes in the peripapillary retinal microvasculature and retinal nerve fibre layer (RNFL) in diabetic participants with various stages of diabetic retinopathy (DR) using swept-source optical coherence tomographic angiography (OCTA).

Design

Community-based, cross-sectional study.

Setting

This study was conducted in a tertiary teaching hospital in Guangzhou, China.

Participants

A total of 1325 ocular-treatment-naive participants, of whom 1115 had no DR and 210 had DR, were recruited in a community in Guangzhou, China.

Primary and secondary outcome measures

A commercially available OCTA device was used to obtain various peripapillary retinal microvascular metrics centred on the optic disc, including vessel density (VD), vessel length

SUBMITTER: Liu J 

PROVIDER: S-EPMC11956287 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature