Peripartum maternal outcomes in individuals with systemic lupus erythematosus in a real-world electronic health record cohort.

ABSTRACT:

Objective

Few studies have examined peripartum maternal outcomes in systemic lupus erythematosus (SLE). Using a de-identified electronic health record (EHR) cohort of individuals with and without SLE, we compared rates of peripartum maternal outcomes including maternal infections, blood transfusions, hospital length of stay, and SLE flares.

Methods

We identified deliveries among individuals with SLE and individuals without autoimmune disease using a previously validated algorithm. Peripartum maternal infection was assessed up to 6 weeks postpartum. Using Chi-square and Mann-Whitney U tests, we compared peripartum outcomes in SLE and control deliveries. We performed mixed effects models to estimate the association of SLE case status with peripartum outcomes. We assessed for S

SUBMITTER: Deffendall C 

PROVIDER: S-EPMC11956324 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature