Optimal risk assessment intervals for primary prevention of cardiovascular disease: a population-based two-stage landmarking study.

ABSTRACT:

Introduction

The recommended assessment intervals for primary prevention of cardiovascular disease (CVD) differ in major international guidelines. We aimed to provide empirical evidence on the optimal frequency of CVD risk assessment to inform future guidelines.

Methods

We estimated the expected time to cross the 10-year CVD risk treatment threshold of 10% using extended two-stage landmarking for more than 2 million people using UK primary care electronic health records between April 2004 and May 2019 from the Clinical Practice Research Datalink GOLD Database (CPRD GOLD), which was linked to hospital admissions data from the Hospital Episodes Statistics (HES) dataset and national mortality records from the Office for National Statistics (ONS). We grouped people based on thei

SUBMITTER: Gu Z 

PROVIDER: S-EPMC11956352 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature