Resolving the observe zone: validation of the ESC 0/3-hour and the APACE criteria for NSTEMI triage.

ABSTRACT:

Background

High-sensitivity cardiac troponin tests have enhanced early myocardial infarction diagnosis, yet many patients still land in the observe zone (OZ). Guidelines suggest a 3-hour troponin measurement for those in the European Society of Cardiology (ESC) 0/1 hour-algorithm's OZ, but evidence on extended troponin testing times and their impact on diagnostic accuracy and outcomes remains sparse.

Methods

Patients with suspected acute coronary syndrome were consecutively enrolled in a single-centre observational study. The triage protocol allowed an optional third troponin measurement at 3 hours or later to evaluate the performance and safety of two validated triage algorithms used to resolve the OZ.

Results

Of the 4605 patients, 948 were triaged to the OZ (20.6%).

SUBMITTER: Reich C 

PROVIDER: S-EPMC11956361 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature