Genome-wide detection of runs of homozygosity in Ding'an pigs revealed candidate genes relating to meat quality traits.

ABSTRACT:

Background

Ding'an (DA) pig, a native Chinese breed, is renowned for its excellent meat quality, disease resistance, high reproductive performance, and adaptability. Its meat quality traits hold significant economic value. However, its conservation population has been declining due to the impact of commercialized breeds and African swine fever, which is not conducive to its development and utilization.

Results

This study utilized whole-genome resequencing data from 15 DA pigs to reveal their genetic characteristics and current resource status. We analyzed the length, number, and distribution patterns of Runs of Homozygosity (ROH) in DA pigs, as well as high-frequency ROH regions. The results identified 23,208,098 single nucleotide polymorphisms (SNPs), 4,497,242 insertion an

SUBMITTER: Wang Z 

PROVIDER: S-EPMC11956453 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature