Benchmarking pathology foundation models for non-neoplastic pathology in the placenta.

ABSTRACT: Machine learning (ML) applications within diagnostic histopathology have been extremely successful. While many successful models have been built using general-purpose models trained largely on everyday objects, there is a recent trend toward pathology-specific foundation models, trained using histopathology images. Pathology foundation models show strong performance on cancer detection and subtyping, grading, and predicting molecular diagnoses. However, we have noticed lacunae in the testing of foundation models. Nearly all the benchmarks used to test them are focused on cancer. Neoplasia is an important pathologic mechanism and key concern in much of clinical pathology, but it represents one of many pathologic bases of disease. Non-neoplastic pathology dominates findings in the placenta,

SUBMITTER: Peng Z 

PROVIDER: S-EPMC11957174 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature