Fast Two-photon Microscopy by Neuroimaging with Oblong Random Acquisition (NORA).

ABSTRACT: Advances in neural imaging have enabled neuroscientists to study how large neural populations conspire to produce perception, behavior and cognition. Despite many advances in optical methods, there exists a fundamental tradeoff between imaging speed, field of view, and resolution that limits the scope of neural imaging, especially for the raster-scanning multi-photon imaging needed to image deeper into the brain. One approach to overcoming this trade-off is computational imaging: the co-development of optics designed to encode the target images into fewer measurements that are faster to acquire, with algorithms that compensate by inverting the optical coding to recover a larger or higher resolution image. We present here one such approach for raster-scanning two-photon imaging: Neuroimagin

SUBMITTER: Whang E 

PROVIDER: S-EPMC11957232 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature