Study of the brain function characteristics in children with cerebral palsy during walking using functional near-infrared spectroscopy.

ABSTRACT:

Significance

Abnormal gait of children with cerebral palsy (CP) is caused by brain damage or developmental defects, exploring the brain's functional characteristics and regulatory mechanisms is essential for rehabilitation.

Aim

We aim to study the brain function characteristics in children with CP during walking.

Approach

The cortical activation, functional connectivity, information flow, and dynamic state transitions of 17 children with CP and 13 healthy children (HC) were analyzed in the resting and walking states.

Results

The motor cortex (MC) of HC is significantly activated in the walking state, whereas both the prefrontal cortex (PFC) and MC of children with CP are significantly activated. The resting brain functional connectivity of children with CP decr

SUBMITTER: Zhang T 

PROVIDER: S-EPMC11957398 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature