Embryos With "No Result" After PGT-A: A Retrospective Analysis of Causative Factors.

ABSTRACT: Background: "No result" after PGT-A is a rare observation. Factors suspected to cause inconclusive diagnoses include poor embryo quality, day of biopsy, biopsy technique, and technical amplification failure due to diluted DNA material. This study aimed to highlight the predisposing factors that could lead to a "no result" observation after PGT-A. Results: This is a retrospective cohort study involving 177 patients and 1335 blastocysts, 1242 of which comprised the control (result) group and 93 comprised the study (no result) group. The predisposing factors studied were the number of blastocysts available for biopsy, the day of biopsy, the grade of the embryo, the degree of expansion of the blastocyst, and the grade of the trophectoderm on biopsy day. The rate of "no result" em

SUBMITTER: Salame A 

PROVIDER: S-EPMC11957852 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature