Epineural stimulation on distal brachial plexus for functional restoration of the upper limb in a primate study.

ABSTRACT: Restoring upper limb function is critical in individuals with central paralysis, and hand control is a priority in patients with neurological impairments. Functional electrical stimulation with implantable electrodes targeting the peripheral nervous system has the potential to selectively recruit hand muscles and generate multiple functional hand movements. However, the implantation of electrodes in the forearm or elbow areas requires multiple incisions for surgery, and elbow joint movements cannot be performed. In this study, we designed and implanted two epineural cuffs on the median and radial nerves in the distal brachial plexus of a single Japanese macaque (Macaca fuscata) monkey. The cuffs were successfully placed via an axillary approach using a single incision. Electrical st

SUBMITTER: Yan T 

PROVIDER: S-EPMC11958176 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature