Bioinformatics revealed biomarkers for diagnosis in kidney stones.

ABSTRACT:

Background

One of the most prevalent urinary illnesses is kidney stone formation, often known as nephrolithiasis. The precise processes of kidney stone remain poorly known after substantial investigation. In order to successfully prevent and cure stone formation and recurrence, additional research into the pathophysiology of stone formation is of paramount importance. Ferroptosis is linked to a variety of renal diseases and is a critical factor in the death of cells. However, little is known about how ferroptosis-related genes (FRGs) contribute to the development of kidney stones.

Methods

The Ferroptosis Database and the Gene Expression Omnibus (GEO) database provided us with information on kidney stones and FRGs, respectively (FerrDb).

Results

Eight DE-FRGs related t

SUBMITTER: He Z 

PROVIDER: S-EPMC11959007 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature