Influential Factors in the Efficacy and Safety of Hemoporfin-Mediated Photodynamic Therapy for Facial Port-Wine Stains.

ABSTRACT:

Background

Hemoporfin-mediated photodynamic therapy (HMME-PDT) is a novel and promising treatment for port-wine stains (PWS); however, the factors affecting the efficacy and safety are controversial.

Aim

In this study, the relationship between influential factors and the efficacy and safety of HMME-PDT for facial PWS was clarified.

Methods

In this retrospective study, 155 patients suffering from facial PWS who underwent HMME-PDT at 2-3 months interval were included. The efficacy was evaluated by the facial PWS area and severity index (FSASI) scoring system based on pre- and post-treatment photographs of the lesion. The demographic characteristics, lesion patterns, treatment history, number of treatment sessions, and adverse events were also recorded.

Results

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SUBMITTER: You R 

PROVIDER: S-EPMC11959330 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature